The Centers for Disease Control and Prevention and the Canadian government knew in 2005 that chloroquine was almost certain to be effective against SARS (beta) Coronaviruses. Five CDC scientists and 3 Canadian scientists told the world about it in 2005 in a popular medical journal. In 2020 they failed to tell you, and our governments restricted its use.
Virology Journal
2005 Aug 22;2:69.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/
Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
1Special Pathogens Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, Georgia, 30333, USA
2Laboratory of Biochemical Neuroendocrinology, Clinical Research Institute of Montreal, 110 Pine Ave West, Montreal, QCH2W1R7, Canada
Corresponding author.
Martin J Vincent: vog.cdc@tnecnivm; Eric Bergeron: ac.cq.mcri@eregreb; Suzanne Benjannet: ac.cq.mcri@snajneb; Bobbie R Erickson: vog.cdc@1noskcirEB; Pierre E Rollin: vog.cdc@nilloRP; Thomas G Ksiazek: vog.cdc@kezaisKT; Nabil G Seidah: ac.cq.mcri@nhadies; Stuart T Nichol: vog.cdc@lohciNS
- Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. mvincent@cdc.gov
- PMID: 16115318
- PMCID: PMC1232869
- DOI: 10.1186/1743-422X-2-69
Background: Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.
Results: We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells…
Conclusion: Chloroquine is effective in preventing the spread of SARS CoV in cell culture…
The infectivity of coronaviruses other than SARS-CoV are also affected by chloroquine, as exemplified by the human CoV-229E [15]. The inhibitory effects observed on SARS-CoV infectivity and cell spread occurred in the presence of 1–10 μM chloroquine, which are plasma concentrations achievable during the prophylaxis and treatment of malaria (varying from 1.6–12.5 μM) [26] and hence are well tolerated by patients…